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LUTALYSE® (dinoprost tromethamine) Sterile Solution was the first natural estrus-synchronization product approved for horses, and it remains unsurpassed today. It makes breeding more convenient, especially when coordinating the use of stallions. LUTALYSE also helps mares with no clinical signs of cycling or irregular estrous cycles become pregnant.


LUTALYSE is indicated for its luteolytic effect in mares. It can be used in the following circumstances:

  • To control the time of estrus in estrous-cycling mares
  • To treat difficult-to-breed mares